Cyclic mechanical strain
WebApr 2, 2024 · In the lungs, vascular endothelial cells experience cyclic mechanical strain resulting from rhythmic breathing motions and intraluminal blood pressure. Mechanical stress creates evident physiological, morphological, biochemical, and gene expression changes in vascular endothelial cells. WebNov 1, 1996 · Cyclic Mechanical Strain Alters Expression of Myosin Isoforms in VSM Cells. To determine the effects of cyclic mechanical strain on the expression of the four myosin isoforms in cultured neonatal …
Cyclic mechanical strain
Did you know?
WebMay 2, 2024 · Purpose. Endothelial progenitor cells (EPCs) have been used as an autologous or allogeneic source in multiple tissue engineering applications. EPCs … WebMay 11, 2009 · The effects of cyclic strain on VSMC migration and the mechanisms involved are poorly understood. Application of 20% strain to cultured VSMCs enhances VSMC migration (Li et al., 2003), which suggests that mechanical strain has a modulating effect on VSMC migration. Our study showed that 10% strain inhibited VSMC migration.
WebSmooth muscle tissue was engineered on two different polymeric scaffolds and subjected to cyclic mechanical strain. Short-term application of strain increased … WebJun 25, 2010 · In nanotoxicology studies, this lung mimic revealed that cyclic mechanical strain accentuates toxic and inflammatory responses of the lung to silica nanoparticles. Mechanical strain also enhances epithelial and endothelial uptake of nanoparticulates and stimulates their transport into the underlying microvascular channel.
WebTools In continuum mechanics, ratcheting, or ratchetting, also known as cyclic creep, is a behavior in which plastic deformation accumulates due to cyclic mechanical or thermal stress. [1] [2] WebThe increase of mean strain and strain amplitude intensifies the cyclic stress relaxation and cyclic softening behaviors. According to the experimental observation, a nonlinear …
WebCyclic mechanical strain was applied during 15 and 60 minutes, respectively. While both, healthy and degenerative tendon cells, responded to strain by an increased proliferation, the cell viability of the degenerative cells was significantly lower compared the healthy cells.
WebThe device could be used to study the cell response to contactless cyclic mechanical stimulation, particularly in TEC with fibroblasts, stromal cells and mesenchymal stem cells, which have been shown to be sensitive to the frequency and strain level at the air-liquid interface. Keywords: 3D printing; Bioreactor ... natur propertyWebDec 1, 2013 · Cyclic mechanical strain effects have been investigated for numerous cell types such as endothelial cells [2], fibroblasts [3] and smooth muscle cells [4]. For … marion iowa building departmentWebCyclic mechanical strain introduced with IL-2 compromised the pulmonary barrier even further and led to a threefold increase in leakage. As expected, the addition of angiopoietin-1 stabilized the endothelial junctions and inhibited IL-2–induced vascular leakage. marion iowa building codesWebThe increase of mean strain and strain amplitude intensifies the cyclic stress relaxation and cyclic softening behaviors. According to the experimental observation, a nonlinear viscoelastic model is proposed to predict the mechanical behavior of butt-joints under cyclic loading, which considers the cyclic stress relaxation and cyclic softening ... marion iowa city codeWebJan 22, 2024 · Physiological cyclic mechanical stretch (10% linear strain, 0.2 Hz) significantly impaired the alveolar epithelial wound healing process relative to culture in static conditions. This impairment could be partially ameliorated by administration of rhHGF. This proof-of-concept study provides a way to study of more complex interactions, such … naturprof ferrolWebSep 10, 2024 · We describe the current strategies and the mechanical properties necessary to promote a positive response in cardiac tissues from different cell sources, distinguishing between passive stimulation, which includes stiffness, topography and static stress and active stimulation, encompassing cyclic strain, compression or perfusion. marion iowa chamber of commerceWebThe cyclic mechanical stress parameters used for our manufactured mechanical loading device ( Figures 1A,B) are as follows: 0.3 and 0.9% elastic strain magnitude, 5-Hz … natur pur an necker und thur