Dual function of vgll4 in muscle regeneration

Author: qnxr

August undefined, 2024

WebMay 25, 2024 · Muscle regeneration is mediated by muscle stem cells, also called satellite cells. Satellite cells are located in a niche between a layer of connective tissue (basal lamina) and muscle fibers (myofibers). ... developed novel gene-editing technologies that could be used to accelerate muscle recovery after injury and improve muscle function ... WebSep 10, 2024 · This opinion is supported by a recent report, which showed that knocking down VGLL4 decreased the skeletal muscle myofiber size [2]. In summary, it is likely …

YAP-VGLL4 antagonism defines the major physiological function …

http://cemcs.cas.cn/kyjz/202408/t20240823_5667038.html WebJul 22, 2024 · muscle regeneration. Results VGLL4 null mice display reduced myofiber size and functional defects in skeletal muscle VGLL4 is a transcriptional suppressor that … stayton ford service

VGLL4 plays a critical role in heart valve development and ... - PLOS

WebDual function of VGLL4 in muscle regeneration. The EMBO journal (July 2024) Vgll4 tm1c(EUCOMM)Hmgu Vgll4 tm1a(EUCOMM)Hmgu: 31328806: Order Mouse and ES … WebAug 14, 2015 · Chargé, Sophie B. P., and Michael A. Rudnicki. Cellular and Molecular Regulation of Muscle Regeneration. Physiol Rev 84: 209–238, 2004; 10.1152/physrev.00019.2003.—Under normal circumstances, mammalian adult skeletal muscle is a stable tissue with very little turnover of nuclei. However, upon injury, skeletal … WebFeb 21, 2024 · Author summary VGLL4, a new member of the Hippo pathway, is intensively investigated in inhibition of tumor progression via competing with YAP to bind TEADs, but its role in cardiovascular field remains unclear. Here we generated VGLL4 knockout mouse line and VGLL4-eGFP reporter mouse line. VGLL4-eGFP reporter mouse line showed … stayton ford

Dual function of VGLL 4 in muscle regeneration

WebDec 21, 2024 · Early insights noted the pattern and sequence of regeneration across species was similar, regardless of the type of injury, and differed from epimorphic limb regeneration. Whil … Key concepts in muscle regeneration: muscle "cellular ecology" integrates a gestalt of cellular cross-talk, motility, and activity to remodel structure and … WebVGLL4 has previously been identified as a negative regulator of YAP. Here we show that VGLL4 regulates muscle regeneration in both YAP-dependent and YAP-independent … stayton fireWebAug 5, 2024 · Mechanisms of muscle repair and regeneration: recent advances Myogenesis during development and injury. In this Subject Collection of The FEBS Journal, we highlight some of the key aspects of muscle repair and regeneration that are important for human health and disease.During development, muscle is produced through the … stayton ford dealership

"WebAug 1, 2024 · (A) Co-immunoprecipitation experiments of TEAD4 with wild-type (WT) VGLL4 or VGLL4 mutant with deletion of two TDU domains in HEK-293T cells. TEAD4 is HAtagged and VGLL4 is FLAG-tagged. " - Dual function of vgll4 in muscle regeneration

Dual function of vgll4 in muscle regeneration

Cellular and Molecular Regulation of Muscle Regeneration

WebJan 16, 2024 · Dual function of VGLL4 in muscle regeneration. EMBO J. 2024; 38 e101051. View in Article Scopus (20) Crossref; Google Scholar; Suo J. Feng X. Zou W. …

Did you know?

WebJul 22, 2024 · Here we show that VGLL4 regulates muscle regeneration in both YAP-dependent and YAP-independent manners at different stages. … WebShu Zhang's 10 research works with 83 citations and 700 reads, including: Dual function of VGLL 4 in muscle regeneration. ... Dual function of VGLL 4 in muscle regeneration.

WebMar 1, 2024 · Therefore, it is important to investigate in the future how VGLL4 cooperates with various regulatory partners to achieve different functions. In addition, VGLL4 is … WebMoreover, our team found that VGLL4 regulated muscle regenera-tion in YAP-dependent manner at the proliferation stage and YAP- independent manner at the differentiation stage (17). Our previous studies suggest that VGLL4 plays an important role to regulate cell differentiation in multiple organs. However, the function of VGLL4

WebMay 25, 2024 · Feng X. et al. Dual function of VGLL4 in muscle regeneration. EMBO J . 38, e101051 (2024). Fu, X. et al. Combination of inflammation-related cytokines … WebPHENOTYPE OF MACROPHAGES DURING MUSCLE REGENERATION: RESOLUTION OF INFLAMMATION. Macrophages are renowned for their heterogeneity, as reflected by the various specialized functions they adopt in different anatomical locations ().Many of these activities seem to be opposing in nature (e.g., proinflammatory vs anti-inflammatory, …

WebMar 1, 2024 · Dual function of VGLL4 in muscle regeneration. EMBO J. (2024) R. Liu et al. Ten-eleven Translocation-2 (TET2) is a master regulator of smooth muscle cell …

WebDownload scientific diagram Analysis of muscle functions in Vgll2 null mice. (a,b) Physical endurance was measured by using a treadmill running test. After acclimation, mice ran on a 10% slope ... stayton fort worth txWebJul 22, 2024 · Europe PMC is an archive of life sciences journal literature. stayton high school attendanceWebMar 17, 2024 · This study entitled as “Dual function of VGLL4 in muscle regeneration” was published in EMBO J on July 22, 2024. FENG Xue, WANG Zuoyun, WANG Fei and … stayton ford stayton orWebDec 15, 2024 · Generation of liver-specific Vgll4 knockout mice . To investigate the role of VGLL4 in development and homeostasis, we generated a conditional knockout allele of Vgll4 (Vgll4 cKO) by inserting two loxP sites flanking exon 3 of the Vgll4 locus through homologous recombination in embryonic stem (ES) cells (Supplemental Fig. S1).A PGK … stayton high school football scheduleWebJul 22, 2024 · Abstract. VGLL4 has previously been identified as a negative regulator of YAP. Here we show that VGLL4 regulates muscle regeneration in both YAP-dependent … stayton high school canvasWebMay 25, 2024 · Muscle regeneration is mediated by muscle stem cells, also called satellite cells. Satellite cells are located in a niche between a layer of connective tissue (basal lamina) and muscle fibers ... stayton heating and coolinghttp://english.cemcs.cas.cn/news/202411/t20241120_252213.html stayton high school mascot