WebFeb 5, 2024 · The Developmental stage of adult human stem cell-derived retinal pigment epithelium cells influences transplant efficacy for vision rescue. Stem Cell Reports 2024;9:42-9. Carr AJ, Vugler AA, Hikita ST, et al. Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat. WebPigment epithelium-derived factor (PEDF) was originally discovered by Joyce Tombran-Tink and Lincoln Johnson in the late 1980s. [8] [9] This group was studying human retinal cell development by identifying secreted factors produced by the retinal pigmented epithelium (RPE), a layer of cells that supports the retina.
National Center for Biotechnology Information
WebApr 27, 2024 · Further lineage tracing analysis showed that these cells are derived from Sox2 + airway epithelial progenitor cells . The potential for these cells to give rise to AT2 and AT1 cells during repair is unclear, and the signaling mechanisms regulating these cells' regenerative responses are incompletely understood. WebEffect of intestinal epithelial cell-derived exosomes on NF-κB reporter activation in THP-1 monocytic cells. The supernatants of the normoxia and hypoxia groups were harvested, and the exosome compartment was extracted. THP-1 Blue NF-κB cells were identically stimulated by the obtained exosomes. contact me on linkedin
Retinal Pigment Epithelial Cells Derived from Induced ... - PubMed
WebMay 9, 2024 · Intestinal epithelial cells (IECs) sense the microbial environment via pattern recognition receptors including toll-like receptors (TLR) and take up diet and microbiota … WebFasudil or N-acetyl-L-cysteine could inhibit the secretion of vascular endothelium-derived NAP-2 and EMT of urothelial cells. ... We previously found that DBP could aberrantly … WebFeb 18, 2024 · Transplantation of stem cell-derived retinal pigment epithelium (RPE) cells is a promising potential therapy for currently incurable retinal degenerative diseases like advanced dry age-related macular degeneration. In this study, we designed a set of clinically applicable devices for subretinal implantation of RPE grafts, towards the overarching … contact me on teams email signature