Ovarian granulosa cell lines
Granulosa cell tumors (GCTs) are a type of ovarian tumor. They often produce hormones and lead to high estrogen levels. Women with a GCT may have irregular periods or bleeding after menopause. In young girls, a GCT may cause early puberty. When healthcare providers diagnose a GCT early, the outlook is … See more Experts don’t entirely understand what causes granulosa cell tumors. They often have a mutation (change) in the FOXL2 gene. FOXL2typically functions to help … See more The most common symptom of a GCT is high estrogen. In girls, high estrogen may cause early puberty. In adults, GCTs commonly cause: 1. Abnormal uterine … See more Without treatment, granulosa cell tumors can increase your risk of other health complications, including: 1. Endometrial hyperplasia, an unusually thick … See more WebOct 16, 2024 · Even though most early stage adult patients with granulosa cell tumors experience an excellent outcome, up to 33% of patients will eventually develop a tumor relapse. ... in 12 AGCT-patient-derived cell lines and an AGCT cell line ... Lonkhuijzen L,, Limpens J, et al. Hormone therapy in ovarian granulosa cell tumors: a systematic review.
Ovarian granulosa cell lines
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WebApr 12, 2024 · This study investigated the roles of adiponectin in IVF treatment during Phase I (the basal stage before gonadotropin administration), Phase II (approximately 8 days … WebApr 11, 2024 · Culture of KGN granulosa cell line. KGN cell line was purchased from MeiSenCTCC company (human KGN cell line, CTCC-003-0105) and maintained in DMEM/F12 medium supplemented with 10% fetal bovine serum (FBS, Gibco, 10,099–141). KGN cell line were cultured at 37 °C in an incubator with 5% CO 2. Establishment of the …
WebMar 30, 2024 · Thus, hormone-sensitive cancers, such as ovarian cancers, are exposed to these compounds. In the present study, we aimed to determine the effects of the concentrations of BPS and BPF found in body fluids on the cell viability, glucose uptake, glycolysis, oxygen consumption, and invasion by the adult ovarian granulosa cell tumor … WebJul 27, 2024 · Cell cultures. The human ovarian granulosa cell lines KGN and COV434 with STR (short tandem repeat) identification were cultured in DMEM (HyClone, Logan, UT, USA) containing 10% fetal bovine serum ...
WebJul 4, 2024 · To further explore the effects of iron overload with EMFF on human ovarian granulosa cell function, we intervened KGN, a human ovarian granulosa cell line, with EMFF and follicular fluid in the ... WebApr 10, 2024 · Furthermore, both APLN-13 and -17 improved the total antioxidant capacity of the ovarian granulosa cells, but such effects were not seen when the cells were …
WebNov 3, 2024 · An Oxidative Stress-Related Gene Signature in Granulosa Cells Is Associated with Ovarian Aging Nuan Lin, 1,2,3Jiazhe Lin, 4Torsten Plosch, 2Pingnan Sun, 1,5,6and Xiaoling Zhou 1,5,6 Academic Editor: Sandra Moreno Received 06 May 2024 Revised 19 Oct 2024 Accepted 21 Oct 2024 Published 03 Nov 2024 Abstract
WebJan 1, 2005 · Ovarian granulosa cell lines Molecular and Cellular Endocrinology Authors: Jon C Havelock William E Rainey Bruce R Carr Request full-text Abstract The ovary is a … cotton salwar suits designsWebIn one model, ovarian granulosa cells isolated from 21-day-old female Sprague Dawley (SD) rats were cultured in vitro for 36 h and exposed to CdCl2 (0, 5, 10, and 20 μM), and in another model, a human ovarian granulosa tumor cell line (COV434) was used to construct the BIP- knockdown cell line sh-BIP and exposed to 0 and 20 μM CdCl2. after ... cottons and satins mumbaiWebFeb 18, 2024 · Cell lines and cell culture. The human ovarian granulosa cell lines KGN and COV434 kept in our laboratory with STR (short tandem repeat) identification were cultured in DMEM (HyClone, USA) supplemented with 1% fetal bovine serum (Gibco, USA) and 100 IU/mL penicillin–streptomycin at 37 °C in a humidified atmosphere of 5% CO 2 … cotton salwar suit readymadeWebApr 12, 2024 · This study investigated the roles of adiponectin in IVF treatment during Phase I (the basal stage before gonadotropin administration), Phase II (approximately 8 days after gonadotropin administration), and Phase III (on the ovum pick-up day), as well as the effects of adiponectin on CYP19A1 and the FSH receptor (FSHR) mRNA expression in a human … breathwork guruWebGranulosa cell tumors (GCTs) are a type of ovarian tumor. They often produce hormones and lead to high estrogen levels. Women with a GCT may have irregular periods or bleeding after menopause. In young girls, a GCT may cause early puberty. When healthcare providers diagnose a GCT early, the outlook is usually good. Symptoms and Causes breathwork grand rapidsWebMar 22, 2024 · FOXL2 and ESR2 are key transcriptional regulators in ovarian granulosa cells. To explore their transcriptional roles and their interplay, we have depleted Foxl2 and Esr2 in mouse primary granulosa cells to assess their ability to bind their targets and/or to modulate gene expression and cellular functions. We show that FOXL2 is involved in a … cottons and satins websiteWebGranulosa cell tumor of the ovary - About the Disease - Genetic and Rare Diseases Information Center National Center for Advancing Translational Sciences Browse by … cottons and sons swansea